Mariola J Ferraro

Mariola J Ferraro,

D.Phil.

Department: AG-MICROBIOLOGY / CELL SCI
Business Phone: (352) 846-0954
Business Email: mjferraro@ufl.edu

Teaching Profile

Courses Taught
2020-2024
MCB5205 Microbiology of Human Pathogens
2022
MCB4934 Special Topics in Microbiology and Cell Science
2018-2024
MCB7980 Research for Doctoral Dissertation
2017-2024
MCB7979 Advanced Research
2016-2024
MCB7922 Journal Colloquy
2020-2024
MCB4203 Bacterial Pathogens
2016-2023
MCB6937 Special Topics in Microbiology
2017-2018,2021-2022
MCB6971 Research for Master’s Thesis
2018,2020-2023,2023
MCB6940 Supervised Teaching
2016-2019
MCB4403 Prokaryotic Cell Structure and Function
2018
GMS7979 Advanced Research
2017-2018
MCB6905 Experimental Microbiology
2018
VME7979 Advanced Research
2018
GMS7980 Research for Doctoral Dissertation
2023-2024
MCB6458 Post Translational Modifications of Proteins in Microbiology

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-0459-7716

Publications

2024
Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis.
NPJ microgravity. 10(1) [DOI] 10.1038/s41526-023-00343-7. [PMID] 38191486.
2024
Changes in lipid composition of host-derived extracellular vesicles following Salmonella infection
Microbiology Spectrum. 12(1) [DOI] 10.1128/spectrum.02796-23. [PMID] 38078720.
2024
Exploring the versatile roles of the endocannabinoid system and phytocannabinoids in modulating bacterial infections
Infection and Immunity. 92(6) [DOI] 10.1128/iai.00020-24. [PMID] 38775488.
2024
Response of Staphylococcus aureus physiology and Agr quorum sensing to low-shear modeled microgravity.
Journal of bacteriology. 206(9) [DOI] 10.1128/jb.00272-24. [PMID] 39120147.
2023
Erratum for Sheppe et al., “Yersinia pseudotuberculosis YopJ Limits Macrophage Response by Downregulating COX-2-Mediated Biosynthesis of PGE2 in a MAPK/ERK-Dependent Manner”
Microbiology Spectrum. 11(3) [DOI] 10.1128/spectrum.03997-22. [PMID] 37022198.
2023
Murine Norovirus Interaction with Enterobacter cloacae Leads to Changes in Membrane Stability and Packaging of Lipid and Metabolite Vesicle Content
Microbiology Spectrum. 11(2) [DOI] 10.1128/spectrum.04691-22. [PMID] 36943087.
2023
Using Activity-Based Proteomics for the Quantification of Deubiquitinases in Animal Tissue.
Methods in molecular biology (Clifton, N.J.). 2591:45-57 [DOI] 10.1007/978-1-0716-2803-4_4. [PMID] 36350542.
2022
Current understanding of extracellular vesicle homing/tropism.
Zoonoses (Burlington, Mass.). 2 [DOI] 10.15212/zoonoses-2022-0004. [PMID] 35601996.
2022
Fluorescent Labeling of Small Extracellular Vesicles (EVs) Isolated from Conditioned Media.
Bio-protocol. 12(12) [DOI] 10.21769/BioProtoc.4447. [PMID] 35864901.
2022
Identification of active deubiquitinases in the chicken tissues
PROTEOMICS. 22(1-2) [DOI] 10.1002/pmic.202100122.
2022
Interaction with mammalian enteric viruses alters outer membrane vesicle production and content by commensal bacteria
Journal of Extracellular Vesicles. 11(1) [DOI] 10.1002/jev2.12172. [PMID] 34981901.
2021
Yersinia pseudotuberculosisYopJ Limits Macrophage Response by Downregulating COX-2-Mediated Biosynthesis of PGE2 in a MAPK/ERK-Dependent Manner
Microbiology Spectrum. 9(1) [DOI] 10.1128/spectrum.00496-21. [PMID] 34319170.
2021
Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo
PLOS Pathogens. 17(5) [DOI] 10.1371/journal.ppat.1009465. [PMID] 33956909.
2021
Characterization and proteomic analysis of outer membrane vesicles from a commensal microbe, Enterobacter cloacae.
Journal of proteomics. 231 [DOI] 10.1016/j.jprot.2020.103994. [PMID] 33007464.
2021
Intravacuolar Pathogens Hijack Host Extracellular Vesicle Biogenesis to Secrete Virulence Factors.
Frontiers in immunology. 12 [DOI] 10.3389/fimmu.2021.662944. [PMID] 33959131.
2021
Roles of Eicosanoids in Regulating Inflammation and Neutrophil Migration as an Innate Host Response to Bacterial Infections
Infection and Immunity. 89(8) [DOI] 10.1128/iai.00095-21.
2020
An atlas of the catalytically active liver and spleen kinases in chicken identified by chemoproteomics.
Journal of proteomics. 225 [DOI] 10.1016/j.jprot.2020.103850. [PMID] 32502695.
2020
CNS-Targeting Therapies for Lysosomal Storage Diseases: Current Advances and Challenges.
Frontiers in molecular biosciences. 7 [DOI] 10.3389/fmolb.2020.559804. [PMID] 33304924.
2020
Exosomes released by breast cancer cells under mild hyperthermic stress possess immunogenic potential and modulate polarization in vitro in macrophages.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 37(1):696-710 [DOI] 10.1080/02656736.2020.1778800. [PMID] 32568583.
2020
Long-term Changes in the Central Amygdala Proteome in Rats with a History of Chronic Cocaine Self-administration.
Neuroscience. 443:93-109 [DOI] 10.1016/j.neuroscience.2020.06.011. [PMID] 32540363.
2020
Modification of the host ubiquitome by bacterial enzymes.
Microbiological research. 235 [DOI] 10.1016/j.micres.2020.126429. [PMID] 32109687.
2019
Adolescent rat social play: Amygdalar proteomic and transcriptomic data.
Data in brief. 27 [DOI] 10.1016/j.dib.2019.104589. [PMID] 31673590.
2019
Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation
Nature Communications. 10(1) [DOI] 10.1038/s41467-019-08605-3. [PMID] 30741923.
2019
Proteomic and transcriptional profiling of rat amygdala following social play.
Behavioural brain research. 376 [DOI] 10.1016/j.bbr.2019.112210. [PMID] 31493430.
2018
Endocannabinoid hydrolases in avian HD11 macrophages identified by chemoproteomics: inactivation by small-molecule inhibitors and pathogen-induced downregulation of their activity.
Molecular and cellular biochemistry. 444(1-2):125-141 [DOI] 10.1007/s11010-017-3237-0. [PMID] 29196970.
2018
PGE2 Augments Inflammasome Activation and M1 Polarization in Macrophages Infected With Salmonella Typhimurium and Yersinia enterocolitica.
Frontiers in microbiology. 9 [DOI] 10.3389/fmicb.2018.02447. [PMID] 30429830.
2018
Proteome-wide lysine acetylation identification in developing rice (Oryza sativa) seeds and protein co-modification by acetylation, succinylation, ubiquitination, and phosphorylation.
Biochimica et biophysica acta. Proteins and proteomics. 1866(3):451-463 [DOI] 10.1016/j.bbapap.2017.12.001. [PMID] 29313810.
2018
Salmonella enterica Serovar Typhimurium Alters the Extracellular Proteome of Macrophages and Leads to the Production of Proinflammatory Exosomes
Infection and Immunity. 86(2) [DOI] 10.1128/iai.00386-17.
2018
SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification.
Genome research. 28(3):396-411 [DOI] 10.1101/gr.222976.117. [PMID] 29440222.
2017
The effects of model aromatic lignin compounds on growth and lipid accumulation of Rhodococcus rhodochrous
International Biodeterioration & Biodegradation. 121:79-90 [DOI] 10.1016/j.ibiod.2017.03.023.
2016
Analysis of differentially expressed proteins in Yersinia enterocolitica-infected HeLa cells.
Biochimica et biophysica acta. 1864(5):562-9 [DOI] 10.1016/j.bbapap.2016.02.004. [PMID] 26854600.
2016
Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?
Mediators of Inflammation. 2016:1-13 [DOI] 10.1155/2016/3481371. [PMID] 27597804.
2016
The Effect of Oxygen on Bile Resistance in Listeria monocytogenes.
Journal of proteomics & bioinformatics. 9(4):107-119 [PMID] 27274623.
2016
Use of focused ultrasonication in activity-based profiling of deubiquitinating enzymes in tissue
Analytical Biochemistry. 515:9-13 [DOI] 10.1016/j.ab.2016.09.016. [PMID] 27663132.

Grants

Apr 2022 ACTIVE
The Function of Host-derived Extracellular Vesicles in Trafficking of Bacterial Antigens to Stimulate the Antibacterial Immune Response
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Oct 2021 – May 2023
Modeling host-microbe interaction under microgravity conditions using Enterobacter model
Role: Principal Investigator
Funding: UNIV OF CENTRAL FLORIDA FL SPACE GRANT via NASA
Jun 2021 – Oct 2021
Sapphire North Americas Return to Research grants
Role: Principal Investigator
Funding: CAYMAN BIOMEDICAL RESEARCH INSTITUTE
Mar 2021 ACTIVE
Assessing the impact of Agr quorum sensing on Staphylococcus aureus physiology in the space flight environment
Role: Co-Investigator
Funding: NASA KENNEDY SPACE FLIGHT CTR
May 2020 – May 2024
Host enzymes as targets of novel host-directed antimicrobial therapies
Role: Principal Investigator
Funding: US ARMY MED RES ACQUISITION
Aug 2019 – Jun 2021
Evaluating and modifying exosome production and content to improve human norovirus cultivation in B cells.
Role: Co-Project Director/Principal Investigator
Funding: ALTERNATIVES RESEARCH & DEVELOPMENT FOU
Jul 2019 – Oct 2021
Exososomal CNS-Delivery of Therapies for a Lysosomal Disorder
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Jun 2019 – Aug 2022
The impact of human norovirus interactions on commensal bacteria
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Jun 2019 – Oct 2022
Function and protein cargo of exosomes in antigen presenting cells during Salmonella infection
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Jun 2019 – May 2022
OR-DRPD-ROF2019: Regulation of exosome production and content resulting from human norovirus infection of B cells.
Role: Co-Project Director/Principal Investigator
Funding: UF RESEARCH
Oct 2018 – Oct 2021
Quorum sensing and S. aureus virulence potential during simulated microgravity growth
Role: Co-Investigator
Funding: NASA STENNIS SPACE FLIGHT CTR
Aug 2018 – Feb 2020
Use of novel magnetic aptamer-based nanoparticles with DNAse-sensitive labels for detection and capture of exosomes followed by omics-based
Role: Principal Investigator
Funding: ALTERNATIVES RESEARCH & DEVELOPMENT FOU
Oct 2017 – Oct 2018
Functions of lipid mediators in innate immune responses to enteric infections
Role: Principal Investigator
Funding: CAYMAN BIOMEDICAL RESEARCH INSTITUTE
Sep 2017 – Aug 2024
Florida Pathways to Success: a research university/minority-serving community college partnership to enhance retention and diversity of transfer students
Role: Project Manager
Funding: NATL SCIENCE FOU
Jan 2017 – Dec 2021
Broadening the STEM Pipeline with Research Experiences in Agricultural Science
Role: Project Manager
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Sep 2016 – Sep 2018
High Throughput Salmonella Detector
Role: Project Manager
Funding: NVE CORPORATION via US DEPT OF AG NATL INST OF FOOD AND AG
Aug 2015 – Oct 2018
Identifying Active Deubiquitinases and Kinases in Chicken
Role: Principal Investigator
Funding: MISSISSIPPI STATE UNIV via US DEPT OF AG NATL INST OF FOOD AND AG
Jul 2015 ACTIVE
UF component for SRI program
Role: Project Manager
Funding: UNIV OF CENTRAL FLORIDA SPACE INST via FL LEGISLATURE

Contact Details

Phones:
Business:
(352) 846-0954
Emails:
Business:
mjferraro@ufl.edu
Addresses:
Business Mailing:
PO BOX 110700
DEPARTMENT OF MICROBIOLOGY AND CELL SCIENCE
GAINESVILLE FL 326110700
Business Street:
1355 MUSEUM RD ROOM 1031/ ROOM 1151
MICROBIOLOGY AND CELL SCIENCE
GAINESVILLE FL 32611